A second opinion should be obtained by a physician for a challenging case in an attempt to arrive at an accurate diagnosis leading to optimal treatment. And second opinions should be requested by patients when diagnoses require life-altering therapy, to ensure accurate diagnoses and proper treatment plans.

Besides, Why would you need a second biopsy?

If the biopsy sample is not sufficient to accurately interpret the findings for a precise diagnosis, it will need to be repeated. This leads to uncertainty and anxiety for the patient and can delay proper treatment,” says Dr.

Keeping this in mind, Should you get a second opinion on a pathology report? Getting a second opinion

It may be helpful to talk with more than one doctor about your diagnosis and treatment plan. This is called a second opinion. It is important to get a copy of the pathology report and any other medical records.

Are pathology reports ever wrong?

The reported frequency of anatomic pathologic errors ranges from 1% to 43% of all specimens, regardless of origin and disease, he said. The error rate for oncology is 1% to 5%.

Can pathology results be wrong?

Although tests aren’t 100% accurate all the time, receiving a wrong answer from a cancer biopsy – called a false positive or a false negative – can be especially distressing. While data are limited, an incorrect biopsy result generally is thought to occur in 1 to 2% of surgical pathology cases.

Can we do biopsy twice?

While it is not regular practice to perform a second biopsy to confirm a diagnosis, physicians sometimes will present especially difficult specimens at subspecialty consensus conferences and at multidisciplinary tumor boards to get other doctors’ opinions and insights.

Can a doctor tell if a tumor is cancerous by looking at it?

Cancer is nearly always diagnosed by an expert who has looked at cell or tissue samples under a microscope. In some cases, tests done on the cells’ proteins, DNA, and RNA can help tell doctors if there’s cancer. These test results are very important when choosing the best treatment options.

What does an inconclusive biopsy mean?

A biopsy is sometimes inconclusive, which means it hasn’t produced a definitive result. In this case, the biopsy may need to be repeated, or other tests may be required to confirm your diagnosis.

Should I get a second opinion on a breast biopsy?

Certainly a second opinion should be obtained before any definitive surgery, like a mastectomy, or a treatment with substantial side effects, such as radiation therapy or chemotherapy. People should not worry too much that a second opinion on their breast pathology will delay treatment.

What can I expect from a second opinion?

The process of seeking a second opinion can be as simple as getting a referral from your current doctor and making sure your health insurance will pay for it. You will need to gather any biopsy or surgery reports, hospital discharge reports, relevant imaging tests, and information on drugs or supplements you take.

Can I ask for a second opinion in hospital?

Asking for a second opinion is not a legal right, but most doctors will be happy to refer you. If you are unsure about anything to do with your diagnosis or treatment, you can always ask for another appointment with your GP or consultant.

Can a biopsy be misdiagnosed?

Biopsy specimens are examined by pathologists, who look at the tissue sample under a microscope in order to determine if it is cancerous. It has been estimated that 1 in every 71 biopsies is misdiagnosed as cancerous when it was not, and 1 out of every 5 cancer cases was misclassified.

Can a punch biopsy be wrong?

Punch biopsy for large melanocytic lesions does have pitfalls. False-negative results can occur using small area biopsies (2-mm or 3-mm punches). Trying to select the most significant area within a large lesion to biopsy can also lead to clinical inaccuracies.

Can a skin biopsy be wrong?

Can a biopsy be wrong? Yes, skin biopsies are like all medical tests. They are not 100% accurate and sometimes a repeat test is needed. Also, skin evolves with time and a repeat test days, weeks, months, or years later may show different results.

Can a prostate biopsy be wrong?

This means that the patient has an abnormal serum Prostate-Specific Antigen (PSA) but the prostate biopsy demonstrates no cancer. But this does not afford the patient the reassurance he expected. Unfortunately, prostate biopsy has a 30-40% false negative rate, requiring many men to undergo the procedure again.

Can a needle biopsy be wrong?

Needle biopsies take a smaller tissue sample and may miss the cancer. However, even with needle biopsies, false negative results are not common. One study looking at nearly 1,000 core needle biopsies found a false negative result rate of 2.2%. That’s just over 2 out of 100 biopsies.

How often should a biopsy be done?

In untreated patients, who do not have risk factors for disease progression, the delay between two biopsies should be at least 4-5 years in order to detect fibrosis progression.

What are the side effects of a biopsy?


Side Effects of Biopsies

  • Pain is the most common side effect.
  • Sometimes a child may get a skin infection at the entry site, but this is very uncommon.
  • Bleeding sometimes occurs under the skin or deep where the needle was placed, causing a black and blue mark.

How long do biopsies take to heal?

How long healing takes varies and depends upon the size and depth of the biopsy, the anatomic site (the face heals much faster than the ankle), and any underlying medical conditions you may have. Most biopsy sites heal within 2 to 3 weeks.

How do you determine if a tumor is benign or malignant?

When the cells in the tumor are normal, it is benign. Something just went wrong, and they overgrew and produced a lump. When the cells are abnormal and can grow uncontrollably, they are cancerous cells, and the tumor is malignant.

Can you tell if a tumor is benign without a biopsy?

Benign tumors can grow but do not spread. There is no way to tell from symptoms alone if a tumor is benign or malignant. Often an MRI scan can reveal the tumor type, but in many cases, a biopsy is required. If you are diagnosed with a benign brain tumor, you’re not alone.

How do you know if a mass is cancerous?

Bumps that are cancerous are typically large, hard, painless to the touch and appear spontaneously. The mass will grow in size steadily over the weeks and months. Cancerous lumps that can be felt from the outside of your body can appear in the breast, testicle, or neck, but also in the arms and legs.

What happens if biopsy results are inconclusive?

A biopsy is sometimes inconclusive, which means it hasn’t produced a definitive result. In this case, the biopsy may need to be repeated, or other tests may be required to confirm your diagnosis.

What does it mean when results are inconclusive?

Listen to pronunciation. (IN-kun-KLOO-siv reh-ZULT) A negative test result in an individual where a clearly deleterious mutation has not been found in any family members.

What does inconclusive in medical terms mean?

Inconclusive or uncertain, which means there wasn’t enough information in the results to diagnose or rule out a disease. If you get an inconclusive result, you will probably get more tests.